Regionalized Vaccine Manufacturing Collaborative A Framework for Enhancing Vaccine Access Through Regionalized Manufacturing EcosystemsI N S I G H T R E P O R TJ A N U A R Y 2 0 2 4In collaboration with DeloitteContentsImages: Getty ImagesForewordExecutive SummaryIntroductionContextRegionalized Vaccine Manufacturing Collaborative (RVMC)RVMC Framework OverviewPillar 1 Business ArchetypesPath to ImplementationStep 1 Select Business Archetype and Positioning StrategyStep 2 Assemble, Test and Scale Minimum Viable Business ModelPillar 2 Healthy Regional MarketsPath to ImplementationStep 1 Aggregate DemandStep 2 Attract SupplyStep 3 Build and Shape Healthy Markets based on Gavi’s Healthy Markets FrameworkStep 4 Optimize and Sustain Regional MarketsPillar 3 Financial ModelsPath to ImplementationStep 1 Conduct Project Feasibility StudiesStep 2 De-risk Financial ReturnsStep 3 Develop Targeted Financial InstrumentsPillar 4 R&D and Manufacturing InnovationPath to ImplementationStep 1 Establish Regional Vaccine Manufacturing Innovation StrategyStep 2 Prioritize and Resource a Portfolio of TechnologiesStep 3 Create and Execute Innovation ProgrammesPillar 5 Technology Transfer and Workforce DevelopmentPath to ImplementationStep 1 Contextualize and Customize the Tech Transfer Process for the Region’s CapabilitiesStep 2 Train the Local Manufacturing Workforce to Receive the TechnologyStep 3 Embed Regulatory & QA/QC Skills46778811111112131313141516171717171819191921212222222424Regionalized Vaccine Manufacturing Collaborative2Pillar 6 Supply Chain and InfrastructurePath to ImplementationStep 1 Design End-to-End Vaccine Supply Chains Right-Sized to the Regional MarketStep 2 Diversify Vaccine Manufacturing OperationsStep 3 Establish Inbound Supply Chains and LogisticsStep 4 Establish Outbound Supply Chain Distribution NetworksStep 5 Implement End-to-End Supply Chain Information Systems, Data Integration and Digital AutomationPillar 7 Product RegulationPath to Implementation: Harmonize Safety and Quality Regulations Across Member StatesPillar 8 Policy and GovernancePath to ImplementationStep 1 Set Governance Strategy and Establish Regional InitiativesStep 2 Implement Regional Policy FrameworkConclusion and OutlookRecapSupply: Access to TechnologyDemand: Access to MarketsCapital: Access to FinancingLooking AheadAcronymsAcknowledgementsEndnotes25252526262728292932323233343434353636383941© 2024 World Economic Forum. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, including photocopying and recording, or by any information storage and retrieval system.Disclaimer This document is published by the World Economic Forum as a contribution to a project, insight area or interaction. The findings, interpretations and conclusions expressed herein are a result of a collaborative process facilitated and endorsed by the World Economic Forum but whose results do not necessarily represent...
